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ZIRC
OBO ID: GO:0004707
Term Name: MAP kinase activity Search Ontology:
Synonyms:
  • ATP:protein phosphotransferase (MAPKK-activated) activity
  • Dp38
  • ERK
  • ERK1
  • ERK2
  • extracellular signal-regulated kinase activity
  • LeMPK3
  • MAP kinase 1 activity
  • MAP kinase 2 activity
  • MAP-2 kinase activity
  • MAPK
  • MBP kinase I activity
  • MBP kinase II activity
  • mitogen activated kinase activity
  • mitogen-activated protein kinase activity
  • MP kinase activity
  • Mpk2
  • myelin basic protein kinase activity
  • p38
  • p38-2
  • p38delta
  • p42 mitogen-activated protein kinase activity
  • p42mapk
  • p44mpk
  • PMK-1
  • PMK-2
  • PMK-3
  • pp42
  • pp44mapk
  • SAPK2
  • STK26
Definition: Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli. 0198547684
References:
  • EC:2.7.11.24
  • KEGG_REACTION:R00162
  • MetaCyc:2.7.11.24-RXN
  • Reactome:R-HSA-111898
  • Reactome:R-HSA-198733
  • Reactome:R-HSA-445079
  • Reactome:R-HSA-451366
  • Reactome:R-HSA-5654560
  • Reactome:R-HSA-5654562
  • Reactome:R-HSA-5654565
  • Reactome:R-HSA-5654566
  • Reactome:R-HSA-73722
  • Reactome:R-HSA-9626832
Ontology: GO: Molecular Function   QuickGO   AmiGO
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