OBO ID: GO:0004663
Term Name: Rab geranylgeranyltransferase activity Search Ontology:
Synonyms:
  • geranylgeranyl-diphosphate,geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity
  • GGTase-II activity
  • GGTaseII activity
  • protein geranylgeranyltransferase type II activity
  • Rab-protein geranylgeranyltransferase activity
  • RabGGTase activity
  • type II protein geranyl-geranyltransferase activity
Definition: Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family. (2)
References:
  • EC:2.5.1.60
  • MetaCyc:RXN-19995
  • MetaCyc:RXN-19996
  • MetaCyc:RXN-19997
Ontology: GO: Molecular Function    QuickGO    AmiGO
PHENOTYPE No data available