OBO ID: GO:0004491

Term Name:	methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity		Search Ontology:
Synonyms:	methylmalonate-semialdehyde dehydrogenase (acylating) activity MMSA dehydrogenase activity MSDH activity
Definition:	Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + CO2 + NADH + H+. Can also use malonate (3-oxopropanoate) as a substrate. The reaction occurs in two steps with the decarboxylation process preceding CoA-binding. Bicarbonate rather than CO2 is released as a final product. (2)
References:	EC:1.2.1.27 MetaCyc:1.2.1.27-RXN Reactome:R-HSA-70893
Ontology:	GO: Molecular Function    QuickGO    AmiGO