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ZIRC
OBO ID: GO:0003906
Term Name: DNA-(apurinic or apyrimidinic site) endonuclease activity Search Ontology:
Synonyms:
  • AP endonuclease class I activity
  • AP site-DNA 5'-phosphomonoester-lyase activity
  • apurinic/apyrimidinic endodeoxyribonuclease activity
  • deoxyribonuclease (apurinic or apyrimidinic) activity
  • DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity
  • endonuclease VIII activity
  • UV endonuclease
Definition: Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER).AP_endonuclease
References:
  • Reactome:R-HSA-110375
  • Reactome:R-HSA-5649711
  • Reactome:R-HSA-5649725
Ontology: GO: Molecular Function   QuickGO   AmiGO
PHENOTYPE No data available