Term Name: |
alkylbase DNA N-glycosylase activity |
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Search Ontology:
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Synonyms: |
- 3-methyladenine DNA glycosylase II
- AlkA
- alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)
- alkylbase DNA glycosidase activity
- deoxyribonucleate 3-methyladenine glycosidase II
- DNA glycosidase II activity
- DNA-3-methyladenine glycosidase II activity
- DNA-3-methyladenine glycosylase II
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Definition: |
Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site.
(3)
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References: |
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Ontology: |
GO: Molecular Function
QuickGO
AmiGO
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