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ZIRC
OBO ID: GO:0000974
Term Name: Prp19 complex Search Ontology:
Synonyms:
  • nineteen complex
  • NTC
  • Prp19/CDC5 complex
Definition: A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p. (2)
References:
Ontology: GO: Cellular Component   QuickGO   AmiGO
EXPRESSION No data available
PHENOTYPE No data available