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ZIRC
OBO ID: GO:0000724
Term Name: double-strand break repair via homologous recombination Search Ontology:
Synonyms:
  • HDR
  • homologous recombinational repair
  • homology-directed repair
  • HRR
  • Rad51-dependent recombinational repair
  • Rhp51-dependent recombinational repair
Definition: The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule. 10357855
References:
Ontology: GO: Biological Process   QuickGO   AmiGO
expand   PHENOTYPE