OBO ID: GO:0000176 |
Term Name: | nuclear exosome (RNase complex) | Search Ontology: | |
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Definition: | A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. (3) | ||
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Ontology: | GO: Cellular Component QuickGO AmiGO |
EXPRESSION
No data available
PHENOTYPE
No data available