ZFIN Human Disease: obesity

OBO ID: DOID:9970

OBO ID: DOID:9970

Term Name:	obesity	Search Ontology:
Synonyms:
Definition:	An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness. https://en.wikipedia.org/wiki/Obesity
References:	EFO:0001073 ICD10CM:E66.9 ICD9CM:278.00 MESH:D009765 NCI:C159658 OMIM:601665 SNOMEDCT_US_2023_03_01:5476005 UMLS_CUI:C0028754
Ontology:	Human Disease ( DOID:9970 )

Relationships

is a type of:	overnutrition overnutrition Show first 5 Terms
has subtype:	morbid obesity morbid obesity Show first 5 Terms

OTHER obesity PAGES

Alliance (1)

GENES INVOLVED

Human Gene	Zebrafish Ortholog	OMIM Term	OMIM Phenotype ID
ADRB3	adrb3a adrb3b	{Obesity, susceptibility to}	601665
AGRP	agrp	{Obesity, late-onset}	601665
		{Leanness, inherited}	601665
ENPP1	enpp1	{Obesity, susceptibility to}	601665
GHRL	ghrl	{Obesity, susceptibility to}	601665
NR0B2	nr0b2b nr0b2a	Obesity, mild, early-onset	601665
POMC	pomca pomcb	{Obesity, early-onset, susceptibility to}	601665
PPARG	pparg	Obesity, severe	601665
SDC3	sdc3	{Obesity, association with}	601665
UCP3	ucp3	{Obesity, severe, and type II diabetes}	601665
CARTPT		{?Obesity, susceptibility to}

ZEBRAFISH MODELS

Fish	Conditions	Citations
AB	increased food availability	Yang et al., 2019
	increased food availability	Zang et al., 2017
	high fat	Yang et al., 2019
	high fat	Zang et al., 2021
	high fat	Zou et al., 2022
	increased food availability, high fat	Landgraf et al., 2017
	high fat	Xiang et al., 2022
	high fat	Matsuoka et al., 2022
	high fat	Carnovali et al., 2017
	increased food availability	Landgraf et al., 2017
	increased food availability	Lodd et al., 2019
	increased food availability, high fat	Zang et al., 2019
	increased food availability, high fat	Oka et al., 2010
	increased food availability	Dandin et al., 2022
	increased food availability	Kaur et al., 2019
WT	increased food availability	Nakayama et al., 2018
	high fat	Nakayama et al., 2020
	high fat	Jeon et al., 2015
	high fat	Koh et al., 2017
	increased food availability	Seebacher et al., 2017
	increased food availability, high fat	Anwer et al., 2022
	increased food availability	Ghaddar et al., 2021
	increased food availability	Montalbano et al., 2016
ym104Tg	high fat	Hsu et al., 2017
zf2023Tg	standard conditions	Song et al., 2007
mitfa^b692/b692; ednrba^b140/b140	increased food availability	Nishimura et al., 2015

PHENOTYPE No data available

CITATIONS (57)