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ZIRC
OBO ID: DOID:3883
Term Name: Lynch syndrome Search Ontology:
Synonyms:
  • COCA 1
  • Hereditary Defective Mismatch Repair syndrome
  • hereditary nonpolyposis colorectal cancer
  • hereditary nonpolyposis colorectal neoplasm
  • HNPCC - hereditary nonpolyposis colon cancer
Definition: An autosomal dominant disease that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers. (2)
References:
  • GARD:9905
  • MESH:D003123
  • NCI2004_11_17:C6725
  • NCI2004_11_17:C8494
  • NCI:C120083
  • NCI:C8494
  • OMIM:PS120435
  • ORDO:144
  • UMLS_CUI:C0009405
  • UMLS_CUI:C1333990
Ontology: Human Disease   (DOID:3883)
OTHER Lynch syndrome PAGES
GENES INVOLVEDNo data available
ZEBRAFISH MODELSNo data available
PHENOTYPE No data available

CITATIONS: None