ZFIN Human Disease: glioblastoma

OBO ID: DOID:3068

OBO ID: DOID:3068

Term Name:	glioblastoma	Search Ontology:
Synonyms:	adult glioblastoma multiforme GBM glioblastoma multiforme grade IV adult Astrocytic tumor primary glioblastoma multiforme spongioblastoma multiforme
Definition:	A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes. (4)
References:	GARD:2491 ICDO:9440/3 MESH:D005909 NCI:C129295 NCI:C39750 NCI:C9094 SNOMEDCT_US_2023_03_01:63634009 UMLS_CUI:C0017636 UMLS_CUI:C0278878 UMLS_CUI:C1514422
Ontology:	Human Disease ( DOID:3068 )

Relationships

is a type of:	malignant astrocytoma malignant astrocytoma Show first 5 Terms
has subtype:	giant cell glioblastoma glioblastoma classical subtype glioblastoma mesenchymal subtype glioblastoma neural subtype glioblastoma proneural subtype ... Show All 7 Terms giant cell glioblastoma glioblastoma classical subtype glioblastoma mesenchymal subtype glioblastoma neural subtype glioblastoma proneural subtype gliosarcoma IDH-wildtype glioblastoma Show first 5 Terms

OTHER glioblastoma PAGES

Alliance (1)

GENES INVOLVED No data available

ZEBRAFISH MODELS

Fish	Conditions	Citations
AB	cancer xenotransplantation	Porčnik et al., 2021
	cancer xenotransplantation	Barbieri et al., 2022
TL	cancer xenotransplantation	Pudelko et al., 2017
TU	cancer xenotransplantation	Nešović et al., 2020
WT	cancer xenotransplantation	Xu et al., 2022
	cancer xenotransplantation	Wehmas et al., 2016
	cancer xenotransplantation	Schnekenburger et al., 2017
	cancer xenotransplantation	Welker et al., 2017
	cancer xenotransplantation	Breznik et al., 2017
	cancer xenotransplantation	Wilms et al., 2021
	cancer xenotransplantation	Lubanska et al., 2022
gl22Tg	cancer xenotransplantation	Hamilton et al., 2016
knu3Tg	cancer xenotransplantation	Pudelko et al., 2018
s843Tg	cancer xenotransplantation	Zeng et al., 2017
sj1Tg	cancer xenotransplantation	Umans et al., 2020
y1Tg	cancer xenotransplantation	Pudelko et al., 2018
	cancer xenotransplantation	Yang et al., 2013
	cancer xenotransplantation	Yang et al., 2014
zf527Tg	cancer xenotransplantation	Zeng et al., 2017
y1Tg + MO1-mitfa	cancer xenotransplantation	Hammarström et al., 2016
hzm5Et; io006Tg	standard conditions	(2)
mitfa^w2/w2; mpv17^a9/a9; y1Tg	cancer xenotransplantation	Umans et al., 2020

PHENOTYPE No data available

CITATIONS (50)