ZFIN Human Disease: adrenoleukodystrophy

OBO ID: DOID:10588

Term Name:	adrenoleukodystrophy		Search Ontology:
Synonyms:	ALD Bronze Schilder disease diffuse sclerosis Encephalitis periaxialis concentrica Encephalitis periaxialis, Schilder's Siemerling-Creutzfeldt Disease sudanophilic cerebral sclerosis X-linked adrenoleukodystrophy
Definition:	A leukodystrophy that disrupts the breakdown of very-long-chain fatty acids resulting in progressive brain damage, failure of the adrenal glands and eventually death. (2)
References:	ICD10CM:E71.52 MESH:D000326 NCI:C61252 OMIM:300100 SNOMEDCT_US_2023_03_01:65389002 UMLS_CUI:C0162309
Ontology:	Human Disease ( DOID:10588 )

Relationships

is a type of:	leukodystrophy X-linked recessive disease leukodystrophy X-linked recessive disease Show first 5 Terms

OTHER adrenoleukodystrophy PAGES

Alliance (1)

GENES INVOLVED

Human Gene	Zebrafish Ortholog	OMIM Term	OMIM Phenotype ID
ABCD1	abcd1	Adrenomyeloneuropathy, adult	300100
		Adrenoleukodystrophy	300100

ZEBRAFISH MODELS

Fish	Conditions	Citations
abcd1^sa509/sa509	standard conditions	(2)
abcd1^zc92/zc92	standard conditions	Raas et al., 2021

PHENOTYPE No data available

CITATIONS (4)