ZFIN Human Disease: central conducting lymphatic anomaly

OBO ID: DOID:0081030

Term Name:	central conducting lymphatic anomaly		Search Ontology:
Synonyms:	lymphatic malformation-7
Definition:	A lymphatic system disease that is characterized by dysfunction of the thoracic duct or cisterna chyli, leading to a retrograde flux of lymphatic fluid or abnormal drainage of lymphatic fluid and that has_material_basis_in heterozygous mutation in the EPHB4 gene on chromosome 7q22. https://pubmed.ncbi.nlm.nih.gov/31263281/
References:	OMIM:617300
Ontology:	Human Disease ( DOID:0081030 )

Relationships

is a type of:	autosomal dominant disease lymphatic system disease autosomal dominant disease lymphatic system disease Show first 5 Terms

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Alliance (1)

GENES INVOLVED

Human Gene	Zebrafish Ortholog	OMIM Term	OMIM Phenotype ID
EPHB4	ephb4a ephb4b	Lymphatic malformation 7	617300

ZEBRAFISH MODELS

Fish	Conditions	Citations
y251Tg; zf3297Tg	standard conditions	Li et al., 2019

PHENOTYPE No data available

CITATIONS (1)