ZFIN Human Disease: familial adenomatous polyposis

OBO ID: DOID:0050424

Term Name:	familial adenomatous polyposis		Search Ontology:
Synonyms:	adenomatous polyposis of the colon
Definition:	An intestinal disease that has_material_basis_in mutations in the APC gene and involves formation of numerous polyps in the epithelium of the large intestine which are initially benign and later transform into colon cancer. (2)
References:	GARD:6408 MESH:D011125 NCI:C3339 OMIM:PS175100 ORDO:733 SNOMEDCT_US_2023_03_01:72900001 UMLS_CUI:C0032580
Ontology:	Human Disease ( DOID:0050424 )

Relationships

is a type of:	autosomal genetic disease intestinal disease autosomal genetic disease intestinal disease Show first 5 Terms
has subtype:	familial adenomatous polyposis 1 familial adenomatous polyposis 2 familial adenomatous polyposis 3 familial adenomatous polyposis 4 familial adenomatous polyposis 1 familial adenomatous polyposis 2 familial adenomatous polyposis 3 familial adenomatous polyposis 4 Show first 5 Terms

OTHER familial adenomatous polyposis PAGES

Alliance (1)

GENES INVOLVED No data available

ZEBRAFISH MODELS

Fish	Conditions	Citations
apc^hu745/+; ia28Tg	standard conditions	Peron et al., 2020

PHENOTYPE No data available

CITATIONS (2)