OBO ID: CHEBI:9754
Term Name: tris Search Ontology:
Synonyms:
  • 1,1,1-tris(hydroxymethyl)methanamine
  • 2-Amino-2-(hydroxymethyl)-1,3-propanediol
  • 2-amino-2-(hydroxymethyl)propane-1,3-diol
  • aminotris(hydroxymethyl)methane
  • THAM
  • Tris
  • Tris amino
  • Tris base
  • Tris buffer
  • tris(hydroxymethyl)aminomethane
  • Tris-base
  • Trizma
  • Trometamol
  • Tromethamine
Definition: A primary amino compound that is tert-butylamine in which one hydrogen attached to each methyl group is replaced by a hydroxy group. A compound widely used as a biological buffer substance in the pH range 7--9; pKa = 8.3 at 20 degreeC; pKa = 7.82 at 37 degreeC.
References:
  • Beilstein:741883
  • CAS:77-86-1
  • DrugBank:DB03754
  • Drug_Central:2771
  • Gmelin:217857
  • KEGG:C07182
  • KEGG:D00396
  • PDBeChem:TRS
  • PMID:22553829
  • Reaxys:741883
  • Wikipedia:Tris
Ontology: Chebi
PHENOTYPE No data available