ZFIN ChEBI: tetrodotoxin

OBO ID: CHEBI:9506

Term Name:	tetrodotoxin		Search Ontology:
Synonyms:	(1R,5R,6R,7R,9S,11R,12R,13S,14S)-14-(hydroxymethyl)-3-imino-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1(7,11).0(1,6)]tetradecane-5,9,12,13,14-pentol Babylonia japonica toxin 1 BJT 1 fugu poison maculotoxin octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol spheroidine tarichatoxin tetrodontoxin Tetrodotoxin tetrodotoxine TTX
Definition:	A quinazoline alkaloid that is a marine toxin isolated from fish such as puffer fish. It has been shown to exhibit potential neutotoxicity due to its ability to block voltage-gated sodium channels.
References:	AGR:IND607175662 Beilstein:4156319 CAS:4368-28-9 DrugBank:DB05232 HMDB:HMDB0258938 KEGG:C11692 KNApSAcK:C00055525 MetaCyc:CPD-19561 PMID:11024497 PMID:22163187 PMID:22412801 PMID:22798951 PMID:23261990 PMID:23661608 PMID:23866757 PMID:23980434 PMID:24121556 PMID:24295175 PMID:24566728 PMID:28648727 PMID:28817087 PMID:31029635 PMID:31833474 PMID:31985136 PMID:32210160 PMID:32415408 PMID:32625458 PMID:32849450 PMID:33276679 PMID:33450969 PMID:33540777 PMID:33651884 PMID:33805908 PMID:33807311 PMID:33830775 PMID:33913398 PMID:33955768 PMID:34067828 PMID:34207879 PMID:34209313 PMID:34273772 PMID:34357955 PMID:34357968 PMID:34437388 PMID:34454925 PMID:9559733 Reaxys:6072946 Wikipedia:Tetrodotoxin
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	azatetracycloalkane oxatetracycloalkane quinazoline alkaloid azatetracycloalkane oxatetracycloalkane quinazoline alkaloid Show first 5 Terms
has_role:	animal metabolite bacterial metabolite marine metabolite neurotoxin voltage-gated sodium channel blocker animal metabolite bacterial metabolite marine metabolite neurotoxin voltage-gated sodium channel blocker Show first 5 Terms
inverse has_functional_parent:	(+/-)-tetrodotoxin (11S,13S)-3-Amino-5,12,13,14-tetrahydroxy-14-(hydroxymethyl)-8,10-dioxa-2-aza-4-azoniatetracyclo[7.3.1.17,11.01,6]tetradec-3-en-9-olate (11s,13s)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene-5,9,12,13,14-pentol Anhydrotetrodotoxin (+/-)-tetrodotoxin (11S,13S)-3-Amino-5,12,13,14-tetrahydroxy-14-(hydroxymethyl)-8,10-dioxa-2-aza-4-azoniatetracyclo[7.3.1.17,11.01,6]tetradec-3-en-9-olate (11s,13s)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene-5,9,12,13,14-pentol Anhydrotetrodotoxin Show first 5 Terms
inverse is_conjugate_acid_of:	tetrodotoxin(1+) tetrodotoxin(1+) Show first 5 Terms
is_conjugate_base_of:	tetrodotoxin(1+) tetrodotoxin(1+) Show first 5 Terms

PHENOTYPE No data available