OBO ID: CHEBI:90851
Term Name: cobimetinib Search Ontology:
Synonyms:
  • [3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]{3-hydroxy-3-[(2S)-piperidin-2-yl]azetidin-1-yl}methanone
  • cobimetinib
  • GDC 0973
  • GDC-0973
  • GDC0973
  • RG 7420
  • RG7420
  • Xl 518
  • Xl-518
  • XL518
Definition: A member of the class of N-acylazetidines obtained by selective formal condensation of the carboxy group of 3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoic acid with the secondary amino group from the azetidine ring of 3-[(2S)-piperidin-2-yl]azetidin-3-ol. An inhibitor of mitogen-activated protein kinase that is used (as its fumarate salt) in combination with vemurafenib for the treatment of patients with unresectable or metastatic melanoma.
References:
Ontology: Chebi
PHENOTYPE No data available