OBO ID: CHEBI:90531
Term Name: sotrastaurin Search Ontology:
Synonyms:
  • 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]-1H-pyrrole-2,5-dione
  • AEB 071
  • AEB-071
  • AEB071
  • sotrastaurin
  • sotrastaurina
  • sotrastaurine
  • sotrastaurinum
Definition: A member of the class of maleimides that is maleimide which is substituted at position 3 by an indol-3-yl group and at position 4 by a quinazolin-4-yl group, which in turn is substituted at position 2 by a 4-methylpiperazin-1-yl group. It is a potent and selective inhibitor of protein kinase C and has been investigated as an immunosuppresant in renal transplant patients.
References:
Ontology: Chebi
PHENOTYPE No data available