Term Name: |
CD437 |
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Search Ontology:
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Synonyms: |
- 6-(3-adamantan-1-yl-4-hydroxyphenyl)naphthalene-2-carboxylic acid
- 6-[4-hydroxy-3-(tricyclo[3.3.1.1(3,7)]dec-1-yl)phenyl]-2-naphthalenecarboxylic acid
- 6-[4-hydroxy-3-(tricyclo[3.3.1.1(3,7)]dec-1-yl)phenyl]naphthalene-2-carboxylic acid
- AHPN
- Apoptosis Activator VI
- Cd 437
- CD-437
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Definition: |
A naphthoic acid that is 6-phenylnaphthylene-2-carboxyic acid in which the phenyl substituent has been substituted at positions 3 and 4 by adamant-1-yl and hydroxy groups, respectively. It acts as a selective agonist of retinoic acid receptor (RAR)gamma and induces cell cycle arrest and apoptosis in various cancer cells.
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References: |
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Ontology: |
ChEBI
(
EBI
)
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