OBO ID: CHEBI:78843
Term Name: CK-666 Search Ontology:
Synonyms:
  • 2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide
  • CK 666
  • CK-0944666
  • CK666
Definition: A member of the class of indoles that is 2-methyltryptamine in which a hydrogen attached to the primary amino group has been replaced by a 2-fluorobenzoyl group. It is a cell-permeable inhibitor of actin assembly mediated by actin-related protein Arp2/3 complex which works by binding to Arp2/3 complex, stabilising the inactive state of the complex and preventing its movement into the active conformation.
References:
Ontology: Chebi
PHENOTYPE No data available