ZFIN ChEBI: loxoprofen

OBO ID: CHEBI:76172

Term Name:	loxoprofen		Search Ontology:
Synonyms:	(+-)-((2-oxocyclopentyl)methyl)hydratropic acid 2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid loxoprofen loxoprofene loxoprofeno loxoprofenum
Definition:	A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted into its active trans-alcohol metabolite following oral administration.
References:	CAS:68767-14-6 Drug_Central:1615 HMDB:HMDB0041920 KEGG:D08149 LINCS:LSM-5054 Patent:EP1767218 Patent:WO2008020270 Reaxys:2860055 Wikipedia:Loxoprofen
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	cyclopentanones monocarboxylic acid cyclopentanones monocarboxylic acid Show first 5 Terms
has_functional_parent:	propionic acid propionic acid Show first 5 Terms
has_role:	antipyretic EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor non-narcotic analgesic non-steroidal anti-inflammatory drug prodrug antipyretic EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor non-narcotic analgesic non-steroidal anti-inflammatory drug prodrug Show first 5 Terms
inverse has_functional_parent:	(2S)-2-(4-{[(1R,2S)-2-hydroxycyclopentyl]methyl}phenyl)propanoic acid (2S)-2-(4-{[(1R,2S)-2-hydroxycyclopentyl]methyl}phenyl)propanoic acid Show first 5 Terms
inverse is_conjugate_base_of:	loxoprofen(1-) loxoprofen(1-) Show first 5 Terms
is_conjugate_acid_of:	loxoprofen(1-) loxoprofen(1-) Show first 5 Terms

PHENOTYPE No data available