ZFIN ChEBI: carglumic acid

OBO ID: CHEBI:71028

Term Name:	carglumic acid		Search Ontology:
Synonyms:	(2S)-2-(carbamoylamino)pentanedioic acid acide carglumique acido carglumico acidum carglumicum Carbaglu Carbamino-L-glutamic acid Carbamylglutamic acid carglumic acid L-N-Carbamoylglutamic acid N-carbamoyl-L-glutamic acid Ureidoglutaric acid
Definition:	A urea that is the N-carbamoyl derivative of L-glutamic acid. An orphan drug used to treat a deficiency in the enzyme N-acetylglutamate synthase, which leads to acute hyperammonaemia.
References:	CAS:1188-38-1 DrugBank:DB06775 Drug_Central:3068 HMDB:HMDB0015673 KEGG:C05829 KEGG:D07130 MetaCyc:N-CARBAMYL-L-GLUTAMATE PMID:15055204 PMID:17421020 PMID:18234091 PMID:18516804 PMID:18604903 PMID:20410539 PMID:21207059 PMID:21225012 PMID:21403788 PMID:21941437 PMID:22858088 Reaxys:1727929 Wikipedia:Carglumic_acid
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	N-acyl-L-glutamic acid ureas N-acyl-L-glutamic acid ureas Show first 5 Terms
has_role:	carbamylphosphate synthetase I activator orphan drug carbamylphosphate synthetase I activator orphan drug Show first 5 Terms
inverse is_conjugate_base_of:	N-carbamoyl-L-glutamate(2-) N-carbamoyl-L-glutamate(2-) Show first 5 Terms
is_conjugate_acid_of:	N-carbamoyl-L-glutamate(2-) N-carbamoyl-L-glutamate(2-) Show first 5 Terms

PHENOTYPE No data available