OBO ID: CHEBI:68558
Term Name: ticagrelor Search Ontology:
Synonyms:
  • (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
  • (1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
  • AZD 6140
  • AZD-6140
  • AZD6140
  • Brilinta
  • ticagrelor
Definition: A triazolopyrimidine that is an adenosine isostere; the cyclopentane ring is similar to ribose and the nitrogen-rich [1,2,3]triazolo[4,5-d]pyrimidine moiety resembles the nucleobase adenine. A platelet aggregation inhibitor which is used for prevention of thromboembolic events in patients with acute coronary syndrome.
References:
  • CAS:274693-27-5
  • Drug_Central:4184
  • HMDB:HMDB0015702
  • KEGG:D09017
  • PMID:22991347
  • Patent:WO2012085665
  • Reaxys:15468079
Ontology: Chebi
PHENOTYPE No data available