OBO ID: CHEBI:64198

Term Name:	dimercaprol		Search Ontology:
Synonyms:	1,2-dimercapto-3-propanol 1,2-dithioglycerol 2,3-dimercapto-1-propanol 2,3-dimercaptol-1-propanol 2,3-dimercaptopropanol 2,3-disulfanylpropan-1-ol 2,3-dithiopropanol 2,3-mercaptopropan-1-ol 2,3-Mercaptopropanol 3-hydroxy-1,2-propanedithiol alpha,beta-dithioglycerol BAL British anti-lewisite British antilewisite dimercaprol dimercaprolum dimercaptopropanol dithioglycerine dithioglycerol sulfactin
Definition:	A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
References:	CAS:59-52-9 DrugBank:DB06782 Drug_Central:3150 KEGG:C02924 KEGG:D00167 PMID:12605205 PMID:14882450 PMID:21006485 PMID:21803782 PMID:9292286 Patent:US2402665 Reaxys:1732058 Wikipedia:Dimercaprol
Ontology:	ChEBI  ( EBI )