ZFIN ChEBI: 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol

OBO ID: CHEBI:64060

Term Name:	3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol		Search Ontology:
Synonyms:	1-(diphenylmethyl)-2-(4-(3-chlorophenyl)-1-piperazinyl)ethanol 3-(4-(3-chlorophenyl)-1-piperazinyl)-1,1-diphenyl-2-propanol 3-(4-(3-chlorophenyl)piperazin-1-yl)-1,1,-diphenyl-2-propanol 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol BRL 15572 BRL-15,572 BRL-15572 BRL15572
Definition:	An N-alkylpiperazine that is 1-(3-chlorophenyl)piperazine carrying a 3,3-diphenyl-2-hydroxyprop-1-yl group at position 4. A selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B, and exhibiting little or no affinity for a range of other receptor types.
References:	CAS:734517-40-9 Chemspider:2887678 LINCS:LSM-1618 PMID:10854905 PMID:11172936 PMID:11249960 PMID:11750791 PMID:19014464 PMID:19182382 PMID:19721332 PMID:19837141 PMID:20385119 PMID:20863828 PMID:21473863 PMID:21699915 PMID:23583574 PMID:24134630 PMID:25502305 PMID:30904722 PMID:9303567 PMID:9303568 PMID:9865532 Reaxys:9004321
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	monochlorobenzenes N-alkylpiperazine N-arylpiperazine secondary alcohol monochlorobenzenes N-alkylpiperazine N-arylpiperazine secondary alcohol Show first 5 Terms
has_role:	geroprotector serotonergic antagonist geroprotector serotonergic antagonist Show first 5 Terms
inverse is_conjugate_acid_of:	4-(3-chlorophenyl)-1-(2-hydroxy-3,3-diphenylpropyl)piperazin-1-ium(1+) 4-(3-chlorophenyl)-1-(2-hydroxy-3,3-diphenylpropyl)piperazin-1-ium(1+) Show first 5 Terms
is_conjugate_base_of:	4-(3-chlorophenyl)-1-(2-hydroxy-3,3-diphenylpropyl)piperazin-1-ium(1+) 4-(3-chlorophenyl)-1-(2-hydroxy-3,3-diphenylpropyl)piperazin-1-ium(1+) Show first 5 Terms

PHENOTYPE No data available