OBO ID: CHEBI:63916

Term Name:	iloprost		Search Ontology:
Synonyms:	(16R,S)-methyl-18,18,19,19-tetradehydro-6a-carbaprostaglandin I2 (5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]hexahydropentalen-2(1H)-ylidene]pentanoic acid iloprost iloprostum
Definition:	A carbobicyclic compound that is prostaglandin I2 in which the endocyclic oxygen is replaced by a methylene group and in which the (1E,3S)-3-hydroxyoct-1-en-1-yl side chain is replaced by a (3R)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl group. A synthetic analogue of prostacyclin, it is used as the trometamol salt (generally by intravenous infusion) for the treatment of peripheral vascular disease and pulmonary hypertension.
References:	CAS:78919-13-8 DrugBank:DB01088 Drug_Central:1422 KEGG:D02721 PMID:14719835 PMID:15232651 PMID:15241524 PMID:19436672 Patent:DE2845770 Patent:US4692464 Reaxys:4329060 Wikipedia:Iloprost
Ontology:	Chebi