OBO ID: CHEBI:63770 |
Term Name: | necrosulfonamide | Search Ontology: | |
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Definition: | A sulfonamide that is a 3-methoxypyrazin-2-yl derivative of (E)-N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide. Necrosulfonamide specifically blocks necrosis downstream of the activation of RIP3 (the receptor-interacting serine-threonine kinase 3), a key signalling molecule in the programmed necrosis (necroptosis) pathway. | ||
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Ontology: | ChEBI ( EBI ) |
PHENOTYPE
No data available