OBO ID: CHEBI:63722

Term Name:	pemetrexed disodium		Search Ontology:
Synonyms:	disodium (2S)-2-({4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}amino)pentanedioate disodium N-{4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamate
Definition:	An organic sodium salt that is the disodium salt of N-{4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT).
References:	CAS:150399-23-8 DrugBank:DB00642 KEGG:D03828 PMID:19137122 PMID:20209614 Patent:CN101411710 Patent:CN101560206 Patent:EP2301909 Patent:EP2334685 Patent:US2009181990 Patent:US2011124861 Patent:US2011196154 Patent:WO2010028105 Patent:WO2011019986 Patent:WO2011064256 Reaxys:8964395
Ontology:	Chebi