OBO ID: CHEBI:63717
Term Name: tenofovir disoproxil Search Ontology:
Synonyms:
  • 9-((R)-2-((bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine
  • bis(POC)PMPA
  • bis({[(propan-2-yloxy)carbonyl]oxy}methyl) ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate
  • PMPA prodrug
  • tenofovir bis(isopropyloxycarbonyloxymethyl) ester
Definition: An organic phosphonate that is the disoproxil ester of tenofovir. A prodrug for tenofovir, an HIV-1 reverse transcriptase inhibitor, tenofovir disoproxil is used as the fumaric acid salt in combination therapy for the treatment of HIV infection.
References:
  • CAS:201341-05-1
  • DrugBank:DB00300
  • Drug_Central:2593
  • Patent:WO5922695
  • Patent:WO9804569
  • Reaxys:9018187
Ontology: Chebi
PHENOTYPE No data available