OBO ID: CHEBI:61049
Term Name: tacrolimus (anhydrous) Search Ontology:
Synonyms:
  • (-)-FK 506
  • (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19
  • 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
  • FK 506
  • FK506
  • Prograf
  • Tacrolimus
  • tacrolimus anhydrous
Definition: A macrolide lactam containing a 23-membered lactone ring, originally isolated from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis.
References:
  • CAS:104987-11-3
  • DrugBank:DB00864
  • KEGG:C01375
  • KEGG:D08556
  • LIPID_MAPS_instance:LMPK04000003
  • PDBeChem:FK5
  • Patent:EP184162
  • Patent:US5665727
  • Reaxys:3647477
  • Reaxys:8821611
Ontology: Chebi
PHENOTYPE No data available