OBO ID: CHEBI:585948
Term Name: felodipine Search Ontology:
Synonyms:
  • (+-)-ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
  • 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
  • 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester
  • ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
  • felodipina
  • felodipine
  • felodipinum
Definition: The mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris.
References:
  • CAS:72509-76-3
  • DrugBank:DB01023
  • Drug_Central:1142
  • KEGG:D00319
  • LINCS:LSM-1447
  • PDBeChem:225
  • PMID:18457386
  • Patent:EP7293
  • Patent:US4264611
  • Reaxys:4331472
  • Wikipedia:Felodipine
Ontology: ChEBI  ( EBI )
PHENOTYPE No data available