OBO ID: CHEBI:4788
Term Name: encainide Search Ontology:
Synonyms:
  • (+-)-2'-[2-(1-methyl-2-piperidyl)ethyl]-p-anisanilide
  • (+-)-4-methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide
  • 4-methoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide
  • 4-Methoxy-N-{2-[2-(1-methyl-piperidin-2-yl)-ethyl]-phenyl}-benzamide
  • 4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide
  • encainida
  • Encainide
  • encainidum
Definition: 4-Methoxy-N-phenylbenzamide in which the hydrogen at the 2 position of the phenyl group is substituted by a 2-(1-methylpiperidin-2-yl)ethyl group. A class Ic antiarrhythmic, the hydrochloride was used for the treatment of severe or life-threatening ventricular arrhythmias, but it was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack and was withdrawn from the market.
References:
  • Beilstein:497572
  • CAS:66778-36-7
  • DrugBank:DB01228
  • Drug_Central:1007
  • KEGG:C06978
  • KEGG:D07894
  • Patent:DE2210154
  • Patent:US3931195
Ontology: Chebi
PHENOTYPE No data available