Community Action Needed: Please respond to the NIH RFI
OBO ID: CHEBI:4759
Term Name: edrophonium chloride Search Ontology:
Synonyms:
  • (3-hydroxyphenyl)dimethylethylammonium chloride
  • 3-hydroxy-N,N-dimethyl-N-ethylanilinium chloride
  • chlorure d'edrophonium
  • cloruro de edrofonio
  • edrophonii chloridum
  • edrophonium chloride
  • ethyl(m-hydroxyphenyl)dimethylammonium chloride
  • N-ethyl-3-hydroxy-N,N-dimethylanilinium chloride
  • N-ethyl-3-hydroxy-N,N-dimethylbenzenaminium chloride
Definition: The chloride salt of edrophonium. A reversible inhibitor of cholinesterase with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes), it is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
References:
Ontology: Chebi
PHENOTYPE No data available