ZFIN ChEBI: N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide

OBO ID: CHEBI:47495

Term Name:	N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide		Search Ontology:
Synonyms:	H 89 H-89 H89 N-(2-{[3-(4-bromophenyl)prop-2-en-1-yl]amino}ethyl)isoquinoline-5-sulfonamide N-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide N-[2-[[3-(4-bromophenyl)-2-propen-1-yl]amino]ethyl]-5-isoquinolinesulfonamide protein kinase inhibitor H89
Definition:	A member of the class of isoquinolines that is the sulfonamide obtained by formal condensation of the sulfo group of isoquinoline-5-sulfonic acid with the primary amino group of N(1)-[3-(4-bromophenyl)prop-2-en-1-yl]ethane-1,2-diamine. It is a protein kinase A inhibitor.
References:	CAS:127243-85-0 Chemspider:3420 DrugBank:DB07995 LINCS:LSM-2608 PMID:19461967 PMID:26596264 PMID:26747511 PMID:26750148 PMID:26807018 PMID:26939705 PMID:28267871 PMID:32031573 PMID:33352792 PMID:33450772 PMID:33820812 PMID:33964190 Reaxys:8160271 Wikipedia:H-89
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	bromobenzenes isoquinolines olefinic compound secondary amino compound sulfonamide bromobenzenes isoquinolines olefinic compound secondary amino compound sulfonamide Show first 5 Terms
has subtype:	(E)-N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide (E)-N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide Show first 5 Terms
has_role:	EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor Show first 5 Terms
inverse is_conjugate_acid_of:	N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide(2+) N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide(2+) Show first 5 Terms
is_conjugate_base_of:	N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide(2+) N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide(2+) Show first 5 Terms

PHENOTYPE No data available