ZFIN ChEBI: lonafarnib

OBO ID: CHEBI:47097

Term Name:	lonafarnib		Search Ontology:
Synonyms:	4-(2-{4-[(11R)-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidin-1-yl}-2-oxoethyl)piperidine-1-carboxamide lonafarnib lonafarnibum SCH 66336
Definition:	A 4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide that has R configuration. It is used as oral farnesyltransferase inhibitor.
References:	CAS:193275-84-2 KEGG:D04768 PDBeChem:336 PMID:10379665 PMID:11120601 PMID:16732721 PMID:17966839 PMID:22620979 PMID:23897869 PMID:25853815 PMID:26033044 PMID:26189433 PMID:26189435 PMID:9810004 Reaxys:8244925 Wikipedia:Lonafarnib
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide 4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide Show first 5 Terms
has_role:	antineoplastic agent EC 2.5.1.58 (protein farnesyltransferase) inhibitor antineoplastic agent EC 2.5.1.58 (protein farnesyltransferase) inhibitor Show first 5 Terms

PHENOTYPE No data available