OBO ID: CHEBI:45906

Term Name:	suramin		Search Ontology:
Synonyms:	8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID 8,8'-{carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]}dinaphthalene-1,3,5-trisulfonic acid Belganyl Naganol Naphuride Suramin
Definition:	A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.
References:	AGR:IND606744035 Beilstein:3230873 Beilstein:8185304 CAS:145-63-1 Chemspider:5168 DrugBank:DB04786 Drug_Central:2966 HMDB:HMDB0015582 KEGG:C07974 LINCS:LSM-5775 PDBeChem:SVR PMID:11549724 PMID:15733555 PMID:15774519 PMID:28457855 PMID:29414872 PMID:30172846 PMID:30393012 PMID:30449075 PMID:30528604 PMID:30543088 PMID:30771091 PMID:31346035 PMID:31409229 PMID:31667504 PMID:31727005 PMID:31803569 PMID:31844000 PMID:7947391 PMID:8769855 Wikipedia:Suramin
Ontology:	ChEBI  ( EBI )