OBO ID: CHEBI:4391
Term Name: demecarium bromide Search Ontology:
Synonyms:
  • (m-hydroxyphenyl)trimethylammonium bromide decamethylenebis(methylcarbamate)
  • 3,3'-{decane-1,10-diylbis[(methylcarbamoyl)oxy]}bis(N,N,N-trimethylanilinium) dibromide
  • bromure de demecarium
  • bromuro de demecario
  • decamethylenebis(m-dimethylaminophenyl-N-methylcarbamate)dimethobromide
  • decamethylenebis(N-methylcarbamic acid m-dimethylaminophenyl ester) bromomethylate
  • demecarii bromidum
  • demecarium bromide
  • N,N'-bis(3-trimethylammoniumphenoxycarbonyl)-N,N'-dimethyldecamethylenediamine dibromide
Definition: The methobromide salt of the N,N'-bis[3-(dimethylamino)phenyl carbamate] derivative of 2,13-diazatetradecane. It is an inhibitor of acetylcholinesterase and pseudocholinesterase, with a long duration of action. It is used in the treatment of chronic open-angle glaucoma: in the eye, it causes constriction of the iris sphincter muscle and the ciliary muscle, facilitating the outflow of the aqueous humor and so reducing intraocular pressure.
References:
Ontology: Chebi
PHENOTYPE No data available