OBO ID: CHEBI:4046

Term Name:	cyproheptadine		Search Ontology:
Synonyms:	1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine 1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine 4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine 4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine 4-Dibenzo[a,d]cyclohepten-5-ylidene-1-methyl-piperidine 5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene ciproheptadina cyproheptadine cyproheptadinum
Definition:	The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
References:	Beilstein:1348386 CAS:129-03-3 DrugBank:DB00434 Drug_Central:765 KEGG:C06935 KEGG:D07765 LINCS:LSM-5419 PMID:10843226 Patent:US3014911 Wikipedia:Cyproheptadine
Ontology:	ChEBI  ( EBI )