ZFIN ChEBI: sitagliptin

OBO ID: CHEBI:40237

Term Name:	sitagliptin		Search Ontology:
Synonyms:	(2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE (3R)-3-amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one MK-0431 sitagliptin sitagliptina sitagliptine sitagliptinum
Definition:	A triazolopyrazine that exhibits hypoglycemic activity.
References:	Beilstein:9962060 CAS:486460-32-6 DrugBank:DB01261 Drug_Central:2448 HMDB:HMDB0015390 KEGG:D08516 LINCS:LSM-5363 PDBeChem:715 PMID:23286208 PMID:23331339 PMID:23432786 PMID:23489256 PMID:23927568 PMID:24039399 PMID:24041927 Reaxys:9962060 Wikipedia:Sitagliptin
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	triazolopyrazine trifluorobenzene triazolopyrazine trifluorobenzene Show first 5 Terms
has_role:	EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor environmental contaminant hypoglycemic agent serine proteinase inhibitor xenobiotic EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor environmental contaminant hypoglycemic agent serine proteinase inhibitor xenobiotic Show first 5 Terms
inverse has_functional_parent:	(1S,2R,5S)-5-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-2-(2,4,5-trifluorophenyl)cyclohexanamine (1S,2R,5S)-5-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-2-(2,4,5-trifluorophenyl)cyclohexanamine Show first 5 Terms

PHENOTYPE No data available