OBO ID: CHEBI:3395

Term Name:	carbidopa		Search Ontology:
Synonyms:	(-)-L-alpha-hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid hydrate (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid monohydrate (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid--water (1/1) (alphaS)-alpha-hydrazino-3,4-dihydroxy-alpha-methylbenzenepropanoic acid monohydrate (S)-(-)-carbidopa hydrate (S)-carbidopa hydrate carbidopa carbidopa hydrate carbidopa monohydrate carbidopum monohydricum L-alpha-(3,4-dihydroxybenzyl)-alpha-hydrazinopropionic acid monohydrate
Definition:	The hydrate of 3-(3,4-dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversion of levodopa to dopamine. It has no antiparkinson activity by itself, but is used in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa.
References:	CAS:38821-49-7 DrugBank:DB00190 KEGG:D00558 PMID:10841799 Patent:DE2062285 Patent:DE2062332 Patent:GB940596 Patent:US3462536
Ontology:	ChEBI  ( EBI )