Term Name: |
tibolone |
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Search Ontology:
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Synonyms: |
- (17R)-17-hydroxy-7alpha-methyl-19-norpregn-5(10)-en-20-yn-3-one
- (7alpha,17alpha)-17-hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one
- (7alpha,17beta)-17-ethynyl-17-hydroxy-7-methylestr-5(10)en-3-one
- 17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-one
- 17alpha-ethynyl-17beta-hydroxy-7alpha-methylestr-5(10)-en-3-one
- tibolona
- tibolone
- tibolonum
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Definition: |
Estran-3-one with a double bond between positions 5 and 10, and bearing both an ethynyl group and a hydroxy group at position 17 (R-configuration). A synthetic steroid hormone drug which acts as an agonist at all five type I steroid hormone receptors, it is used in the prevention of postmenopausal osteoporosis and for treatment of endometriosis.
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References: |
- CAS:5630-53-5
- Drug_Central:2655
- KEGG:D01639
- Patent:US3340279
- Patent:US3475465
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Ontology: |
ChEBI
(
EBI
)
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