OBO ID: CHEBI:31588
Term Name: fabesetron Search Ontology:
Synonyms:
  • (+)-(R)-8,9-dihydro-10-methyl-7-((5-methylimidazol-4-yl)methyl)pyrido[1,2-a]indol-6(7H)-one
  • (7R)-10-methyl-7-[(5-methyl-1H-imidazol-4-yl)methyl]-8,9-dihydropyrido[1,2-a]indol-6(7H)-one
  • fabesetron
  • fabesetronum
  • FK 1052
  • FK-1052
  • FK1052
Definition: An organic heterotricyclic compound that is 8,9-dihydropyrido[1,2-a]indol-6(7H)-one substituted by a (5-methyl-1H-imidazol-4-yl)methyl group at position 7R and a methyl group at position 10. It is a dual 5-HT3 and 5-HT4 receptors antagonist whose clinical development was terminated in phase II. It was being developed for the treatment of chemotherapy-induced emesis and irritable bowel syndrome.
References:
Ontology: Chebi
PHENOTYPE No data available