OBO ID: CHEBI:31521
Term Name: doxifluridine Search Ontology:
Synonyms:
  • 1-(beta-D-5-desoxyribofuranoxyl)-5-fluoruracil
  • 5'-deoxy-5-fluorouridine
  • 5'-DFUR
  • 5'-dFUrd
  • 5-fluoro-5'-deoxyuridine
  • doxifluridina
  • Doxifluridine
  • doxifluridinum
  • Furtulon
  • Ro 21-9738
  • Ro 219738
Definition: A pyrimidine 5'-deoxyribonucleoside that is 5-fluorouridine in which the hydroxy group at the 5' position is replaced by a hydrogen. It is an oral prodrug of the antineoplastic agent 5-fluorouracil. Designed to circumvent the rapid degradation of 5-fluorouracil by dihydropyrimidine dehydrogenase in the gut wall, it is converted into 5-fluorouracil in the presence of pyrimidine nucleoside phosphorylase.
References:
Ontology: Chebi
PHENOTYPE No data available