ZFIN ChEBI: vincristine

OBO ID: CHEBI:28445

Term Name:	vincristine		Search Ontology:
Synonyms:	(+)-Vincristine 22-oxo-vincaleukoblastine 22-oxovincaleukoblastine leucristine leurocristine oncovin vincristin Vincristine vinkristin
Definition:	A vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer.
References:	Beilstein:4779289 CAS:57-22-7 DrugBank:DB00541 Drug_Central:2825 HMDB:HMDB0014681 KEGG:C07204 KEGG:D08679 KNApSAcK:C00001783 MetaCyc:CPD-19894 PMID:18520608 PMID:30277559 PMID:30429697 PMID:30599272 PMID:30604513 PMID:30657998 PMID:31048222 PMID:31161774 PMID:31214762 PMID:31296986 Wikipedia:Vincristine
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	acetate ester formamides methyl ester organic heteropentacyclic compound organic heterotetracyclic compound ... Show All 8 Terms acetate ester formamides methyl ester organic heteropentacyclic compound organic heterotetracyclic compound tertiary alcohol tertiary amino compound vinca alkaloid Show first 5 Terms
has_parent_hydride:	vincaleukoblastine vincaleukoblastine Show first 5 Terms
has_role:	antineoplastic agent drug microtubule-destabilising agent plant metabolite tubulin modulator antineoplastic agent drug microtubule-destabilising agent plant metabolite tubulin modulator Show first 5 Terms
inverse is_conjugate_acid_of:	vincristine(2+) vincristine(2+) Show first 5 Terms
is_conjugate_base_of:	vincristine(2+) vincristine(2+) Show first 5 Terms

PHENOTYPE No data available