OBO ID: CHEBI:2825
Term Name: aristolochic acid Search Ontology:
Synonyms:
  • 3,4-methylenedioxy-8-methoxy-10-nitro-1-phenanthrenecarboxylic acid
  • 8-methoxy-6-nitrophenanthol (3,4-d) 1,3-dioxole-5-carboxylic acid
  • 8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid
  • Aristolochic acid
  • aristolochic acid A
  • Aristolochic acid I
  • aristolochic acid-I
  • aristolochin
Definition: A monocarboxylic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
References:
Ontology: Chebi
PHENOTYPE No data available