OBO ID: CHEBI:20689
Term Name: 6-O-methylguanine Search Ontology:
Synonyms:
  • 2-Amino-6-methoxypurine
  • 6-Methoxy-1H-purine-2-amine
  • 6-methoxy-7H-purin-2-amine
  • 6-Methoxyguanine
  • O(6)-methylguanine
  • O-(6)-Methylguanine
Definition: A methylguanine in which the methyl group is positioned on the oxygen at position 6. Formed in DNA by alkylation of the oxygen atom of guanine, most often by N-nitroso compounds and sometimes due to methylation by other compounds such as endogenous S-adenosylmethionine, it base-pairs to thymine rather than cytidine, causing a G:C to A:T transition in DNA.
References:
Ontology: ChEBI  ( EBI )
PHENOTYPE No data available