OBO ID: CHEBI:192710

Term Name:	SM-164		Search Ontology:
Synonyms:	(3S,6S,10aS)-6-{[(2S)-2-(methylamino)propanoyl]amino}-N-[(S)-(1-{4-[4-(4-{4-[(S)-({[(3S,6S,10aS)-6-{[(2S)-2-(methylamino)propanoyl]amino}-5-oxodecahydropyrrolo[1,2-a]azocin-3-yl]carbonyl}amino)(phenyl)methyl]-1H-1,2,3-triazol-1-yl}butyl)phenyl]butyl}-1H-1 SM 164 SM164
Definition:	A potent cell-permeable and bivalent Smac mimetic which binds to XIAP, cIAP-1 and cIAP-2 proteins (Ki = 0.56 nM, 0.31 nM and 1.1 nM, respectively). It induces apoptosis and tumor regression in cancer xenograft models.
References:	CAS:957135-43-2 PMID:17999504 PMID:19010913 PMID:21282353 PMID:21372226 PMID:21462933 PMID:21901386 PMID:22148838 PMID:23142291 PMID:23240027 PMID:23699656 PMID:31059038 PMID:32332865 PMID:35525732
Ontology:	ChEBI  ( EBI )