OBO ID: CHEBI:192545
Term Name: LY 379268 Search Ontology:
Synonyms:
  • (1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid
  • LY-379,268
  • LY-379268
  • LY379268
Definition: An organic heterobicyclic compound that is (1R,5S)-2-oxabicyclo[3.1.0]hexane carrying amino, carboxy, and carboxy groups at positions 4R, 4R and 6R, respectively. It is a potent agonist of group II metabotropic glutamate receptors mGluR2 and mGluR3 (EC50 = 2.69 nM and 4.48 nM, respectively) that exhibits antipsychotic-like action in animal models of schizophrenia.
References:
Ontology: ChEBI  ( EBI )
PHENOTYPE No data available