OBO ID: CHEBI:183641
Term Name: 2,8-dihydroxyadenine Search Ontology:
Synonyms:
  • 2,8-DHA
  • 6-amino-2,8-dihydroxypurine
  • 6-amino-9H-purine-2,8-diol
  • 6-amino-purine-2,8-diol
Definition: A member of the class of 6-aminopurines that is adenine bearing two hydroxy substituents at positions 2 and 8. It is a highly insoluble metabolite of adenine that causes radiolucent urolithiasis. It is produced by individuals who suffer from adenine phosphoribosyltransferase (APRT) deficiency, a rare autosomal recessive error of purine metabolism.
References:
Ontology: ChEBI  ( EBI )
Relationships
is a type of:
has_functional_parent:
has_role:
inverse is_tautomer_of:
is_tautomer_of:
PHENOTYPE No data available

Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.