OBO ID: CHEBI:183517
Term Name: LFM-A13 Search Ontology:
Synonyms:
  • (2Z)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide
  • (2Z)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide
  • 2Z-cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide
  • alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl)propenamide
  • DDE-28
Definition: An enamide obtained by formal condensation of the carboxy group of (2Z)-2-cyano-3-hydroxybut-2-enoic acid with the amino group of 2,5-dibromoaniline. It is a dual-function inhibitor of Bruton's tyrosine kinase (BTK) and Polo-like kinases (PLK) that exhibits anticancer properties.
References:
Ontology: Chebi
PHENOTYPE No data available